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Matt Merguerian M D Ph D

Matthew Douglas Merguerian, M.D., Ph.D. Instructor of Pediatrics Specializes in: Adolescents (12-18 years), Children (1-11 years), Infants (up to 1 year)

Expertise

Anemias, Bleeding Disorders, Bone Marrow Failure

Research Interests

Platelet Function Disorders; Inherited

Background

Dr. Matthew Merguerian is an instructor of pediatrics at the Johns Hopkins University School of Medicine. At the NIH in Bethesda, MD, he continues the research he started as a fellow in the laboratory of Dr. Paul Liu at the National Human Genome Research Institute. He is an associate investigator on the NIH natural history study of families with germline RUNX1 mutation, a condition which causes thrombocytopenia, platelet dysfunction, and increased risk of developing hematologic malignancy. He is also studying how gene mutations affect the development of myeloid leukemia in a mouse model of inversion(16) leukemia. Matthew grew up in Toms River, NJ. He attended the University of Chicago as an undergraduate, finishing in 2006 with concentrations in chemistry and biology. As an undergraduate researcher in the lab of Dr. Shohei Koide, Matthew studied how proteins bind to each other using NMR spectroscopy, and how point mutations could interfere with binding function. Matthew was then selected for an NIH NIGMS-funded spot in the Medical Scientist Training Program at Columbia University in New York City. There he earned his medical degree at the Columbia College of Physicians and Surgeons, and he completed his doctoral studies in the laboratory of Dr. Virginia Cornish in the Department of Chemistry. In his doctoral research, he engineered a genetic system in yeast that could discover useful new binding proteins through a process of directed evolution. Dr. Merguerian then moved to New Haven, CT, where he trained in pediatrics as a resident at the Yale School of Medicine. He spent a research elective in the laboratory of Dr. Patrick Gallagher studying the GATA1 transcription factor. Dr. Merguerian then trained as a fellow in pediatric hematology/oncology at the combined Johns Hopkins / NIH program. In 2021, he joined the faculty of the Division of Pediatric Hematology in the Department of Pediatrics at the Johns Hopkins University School of Medicine. Dr. Merguerian has been a board-certified pediatrician since 2018 and has held a medical license in the state of Maryland since 2017. Dr. Merguerian lives in Baltimore, MD, with his wife and two sons.

Titles

Instructor of Pediatrics

Departments Divisions

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Centers & Institutes

Hemophilia Comprehensive Treatment Center

Education

Degrees

MD PhD; Columbia University College of Physicians and Surgeons (2014)

Residencies

Pediatrics; Yale-New Haven Hospital (2017)

Fellowships

Pediatric Hematology-Oncology; Johns Hopkins University School of Medicine (2020) Pediatric Hematology-Oncology; National Institutes of Health (2021)

Board Certifications

American Board of Pediatrics (Pediatrics) (2018)

Research & Publications

Research Summary

Dr. Merguerian's research focuses on genetic diseases that affect the production and function of platelets.

Clinical Trial Keywords

Germline RUNX1 Deficiency; Familial Platelet Disorder

Clinical Trials

ClinicalTrials.gov Identifier:

Contact for Research Inquiries

720 Rutland Avenue
Ross 1125
Baltimore, MD 21205
Phone: 410-955-6132
Fax: 570-473-5316

Academic Affiliations & Courses

Courses and Syllabi

Organic Chemistry
Columbia University, New York, NY
2008 - 2008

Activities & Honors

Honors

Physician Scientist Training Program Scholar, Johns Hopkins University, 2018 Medical Scientist Training Program, NIH NIGMS, 2008 - 2011 Frances E. Knock Prize for Outstanding Academic Achievement in Chemistry, University of Chicago, 2006 Howard Hughes Undergraduate Summer Research Fellowship, HHMI, 2004 Robert C. Byrd Honors Scholarship, U.S. Dept. of Ed., 2002 Dean's List, University of Chicago, 2003 - 2006

Memberships

American Academy of Pediatrics, 2017
Fellow of the AAP